Implications
Approximately, one in every 200 patients treated with any of the three most potent statins can be expected to get diabetes. The data available was only for five years of treatment; it could potentially get worse with longer statin therapy.
- The concern is that if there were a major suppression of heart attacks or strokes or deaths its consumption is justifiable, but patients who have never had heart disease, the reduction of heart attacks and other major events is only two per hundred cases. Hence the benefit achieved, compared to diabetes risk is very low.
- The use of statins in such patients should thus be carefully reviewed, and only the minimal dose required should be prescribed.
- Lifestyle modifications should be encouraged as first course of treatment for lowering cholesterol.
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