Isoflavones possess both a weak estrogenic and anti-estrogenic activity. The anti-estrogenic ability blocks entry of estrogen into cancer receptors and thus protects women from developing breast or endometrial cancer. Pre-menopausal women are benefited eating soy since their estrogen levels are high. But the effect is not same in post menopausal women and excess soy intake can increase the risk of cancer.
Emerging evidence suggests that soy intake reduces cancer risk in Asian (China, Japan) but not in Western populations. This variation is ascribed to the form of isoflavones obtained in Asian and Western diets. The isoflavones from tofu, miso (soy paste), natto (fermented soy) and soymilk are better than just soy protein or flour added to foods. Moreover, early exposure to soy isoflavones from the prenatal, infancy, childhood and pubertal age can alter gene expression and suppress the risk of cancer in women.
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